Adaptive Immunity against Leishmania Nucleoside Hydrolase Maps Its C-Terminal Domain as the Target of the CD4+ T Cell–Driven Protective Response

Nucleoside hydrolases (NHs) show homology among parasite protozoa, fungi and bacteria. They are vital protagonists in the establishment of early infection and, therefore, are excellent candidates for the pathogen recognition by adaptive immune responses. Immune protection against NHs would prevent d...

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Detalles Bibliográficos
Autores principales: Nico, Dirlei, Claser, Carla, Borja-Cabrera, Gulnara P., Travassos, Luiz R., Palatnik, Marcos, da Silva Soares, Irene, Rodrigues, Mauricio Martins, Palatnik-de-Sousa, Clarisa B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976684/
https://www.ncbi.nlm.nih.gov/pubmed/21085470
http://dx.doi.org/10.1371/journal.pntd.0000866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976684/
https://www.ncbi.nlm.nih.gov/pubmed/21085470
http://dx.doi.org/10.1371/journal.pntd.0000866

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