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Controlled expression of functional miR-122 with a ligand inducible expression system

BACKGROUND: To study the biological function of miRNAs, and to achieve sustained or conditional gene silencing with siRNAs, systems that allow controlled expression of these small RNAs are desirable. Methods for cell delivery of siRNAs include transient transfection of synthetic siRNAs and expressio...

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Detalles Bibliográficos
Autores principales: Shea, Cathy M, Tzertzinis, George
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976731/
https://www.ncbi.nlm.nih.gov/pubmed/20961424
http://dx.doi.org/10.1186/1472-6750-10-76