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Controlled expression of functional miR-122 with a ligand inducible expression system
BACKGROUND: To study the biological function of miRNAs, and to achieve sustained or conditional gene silencing with siRNAs, systems that allow controlled expression of these small RNAs are desirable. Methods for cell delivery of siRNAs include transient transfection of synthetic siRNAs and expressio...
Autores principales: | Shea, Cathy M, Tzertzinis, George |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976731/ https://www.ncbi.nlm.nih.gov/pubmed/20961424 http://dx.doi.org/10.1186/1472-6750-10-76 |
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