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Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
BACKGROUND: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-receptors, which interact primarily with the third hypervariable loop (V3 loop) of gp120. Determination of HIV-1 affinity for ei...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976756/ https://www.ncbi.nlm.nih.gov/pubmed/20923564 http://dx.doi.org/10.1186/1471-2105-11-494 |