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Subdivision of the MDR superfamily of medium-chain dehydrogenases/reductases through iterative hidden Markov model refinement

BACKGROUND: The Medium-chain Dehydrogenases/Reductases (MDR) form a protein superfamily whose size and complexity defeats traditional means of subclassification; it currently has over 15000 members in the databases, the pairwise sequence identity is typically around 25%, there are members from all k...

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Detalles Bibliográficos
Autores principales: Hedlund, Joel, Jörnvall, Hans, Persson, Bengt
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976758/
https://www.ncbi.nlm.nih.gov/pubmed/20979641
http://dx.doi.org/10.1186/1471-2105-11-534