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Mantle cell lymphoma salvage regimen: synergy between a reprogrammed oncolytic virus and two chemotherapeutics
MV-PNP H(blind)antiCD20 is a CD20-targeted and prodrug convertase-armed measles virus (MV) that temporarily controls growth of lymphoma xenografts in SCID mice in combination with fludarabine phosphate. Herein, we examine the replication of this targeted virus and of a vaccine-lineage MV in disease...
Autores principales: | Ungerechts, Guy, Frenzke, Marie E, Yaiw, Koon-Chu, Miest, Tanner, Johnston, Patrick B, Cattaneo, Roberto |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976793/ https://www.ncbi.nlm.nih.gov/pubmed/20686506 http://dx.doi.org/10.1038/gt.2010.103 |
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