Radiosensitization of glioma cells by modulation of Met signalling with the hepatocyte growth factor neutralizing antibody, AMG102

The hepatocyte growth factor (HGF)/Met signalling pathway is up-regulated in many cancers, with downstream mediators playing a role in DNA double strand break repair. Previous studies have shown increased radiosensitization of tumours through modulation of Met signalling by genetic methods. We inves...

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Detalles Bibliográficos
Autores principales: Buchanan, Ian M, Scott, Tamalee, Tandle, Anita T, Burgan, William E, Burgess, Teresa L, Tofilon, Philip J, Camphausen, Kevin
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976812/
https://www.ncbi.nlm.nih.gov/pubmed/20629992
http://dx.doi.org/10.1111/j.1582-4934.2010.01122.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976812/
https://www.ncbi.nlm.nih.gov/pubmed/20629992
http://dx.doi.org/10.1111/j.1582-4934.2010.01122.x

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