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Modifiers of notch transcriptional activity identified by genome-wide RNAi

BACKGROUND: The Notch signaling pathway regulates a diverse array of developmental processes, and aberrant Notch signaling can lead to diseases, including cancer. To obtain a more comprehensive understanding of the genetic network that integrates into Notch signaling, we performed a genome-wide RNAi...

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Detalles Bibliográficos
Autores principales: Mourikis, Philippos, Lake, Robert J, Firnhaber, Christopher B, DeDecker, Brian S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976970/
https://www.ncbi.nlm.nih.gov/pubmed/20959007
http://dx.doi.org/10.1186/1471-213X-10-107