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Antiretroviral therapy abrogates association between arginase activity and HIV disease severity()

Arginase-induced L-arginine deprivation is emerging as a key mechanism for the downregulation of immune responses. We hypothesised that arginase activity increases with disease severity in HIV-seropositive patients. Our results show that peripheral blood mononuclear cells (PBMCs) from 23 HIV-seropos...

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Detalles Bibliográficos
Autores principales: Cloke, T.E., Abebe, T., Hailu, A., Munder, M., Taylor, G.P., Müller, I., Kropf, P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977531/
https://www.ncbi.nlm.nih.gov/pubmed/20843532
http://dx.doi.org/10.1016/j.trstmh.2010.08.004