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2-Methyl-1,10b-dihydro-5H-pyrazolo[1,5-c][1,3]benzoxazin-5-one

In the title compound, C(11)H(10)N(2)O(2), a potential inhibitor of the cyclo­oxygenase-2 isoenzyme, the pyrazoline ring exists in a flat-envelope conformation while the puckering of the central oxazine ring is more severe. As a result, the mol­ecule as a whole is non-planar. The formal sp (3) pyraz...

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Detalles Bibliográficos
Autores principales: Kettmann, Viktor, Světlík, Jan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977679/
https://www.ncbi.nlm.nih.gov/pubmed/21584022
http://dx.doi.org/10.1107/S1600536809012173