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The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain

FERM domains are found in a diverse superfamily of signaling and adaptor proteins at membrane interfaces. They typically consist of three separately folded domains (F1, F2, F3) in a compact cloverleaf structure. The crystal structure of the N-terminal head of the integrin-associated cytoskeletal pro...

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Detalles Bibliográficos
Autores principales: Elliott, Paul R., Goult, Benjamin T., Kopp, Petra M., Bate, Neil, Grossmann, J. Günter, Roberts, Gordon C.K., Critchley, David R., Barsukov, Igor L.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977851/
https://www.ncbi.nlm.nih.gov/pubmed/20947018
http://dx.doi.org/10.1016/j.str.2010.07.011