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MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake

Mitochondrial calcium uptake plays a central role in cell physiology by stimulating ATP production, shaping cytosolic calcium transients, and regulating cell death. The biophysical properties of mitochondrial calcium uptake have been studied in detail, but the underlying proteins remain elusive. Her...

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Detalles Bibliográficos
Autores principales: Perocchi, Fabiana, Gohil, Vishal M., Girgis, Hany S., Bao, X. Robert, McCombs, Janet E., Palmer, Amy E., Mootha, Vamsi K.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977980/
https://www.ncbi.nlm.nih.gov/pubmed/20693986
http://dx.doi.org/10.1038/nature09358