Phosphoproteomics-Based Modeling Defines the Regulatory Mechanism Underlying Aberrant EGFR Signaling

BACKGROUND: Mutation of the epidermal growth factor receptor (EGFR) results in a discordant cell signaling, leading to the development of various diseases. However, the mechanism underlying the alteration of downstream signaling due to such mutation has not yet been completely understood at the syst...

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Detalles Bibliográficos
Autores principales: Tasaki, Shinya, Nagasaki, Masao, Kozuka-Hata, Hiroko, Semba, Kentaro, Gotoh, Noriko, Hattori, Seisuke, Inoue, Jun-ichiro, Yamamoto, Tadashi, Miyano, Satoru, Sugano, Sumio, Oyama, Masaaki
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978091/
https://www.ncbi.nlm.nih.gov/pubmed/21085658
http://dx.doi.org/10.1371/journal.pone.0013926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978091/
https://www.ncbi.nlm.nih.gov/pubmed/21085658
http://dx.doi.org/10.1371/journal.pone.0013926

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