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Identification and structural analysis of C-terminally truncated collapsin response mediator protein-2 in a murine model of prion diseases
BACKGROUND: Prion diseases are fatal neurodegenerative disorders that accompany an accumulation of the disease-associated form(s) of prion protein (PrP(Sc)) in the central nervous system. The neuropathological changes in the brain begin with focal deposits of PrP(Sc), followed by pathomorphological...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978134/ https://www.ncbi.nlm.nih.gov/pubmed/20961402 http://dx.doi.org/10.1186/1477-5956-8-53 |