Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

BACKGROUND: Pim family kinases are small constitutively active serine/threonine-specific kinases, elevated levels of which have been detected in human hematopoietic malignancies as well as in solid tumours. While we and others have previously shown that the oncogenic Pim kinases stimulate survival o...

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Detalles Bibliográficos
Autores principales: Santio, Niina M, Vahakoski, Riitta L, Rainio, Eeva-Marja, Sandholm, Jouko A, Virtanen, Sanna S, Prudhomme, Michelle, Anizon, Fabrice, Moreau, Pascale, Koskinen, Päivi J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978147/
https://www.ncbi.nlm.nih.gov/pubmed/20958956
http://dx.doi.org/10.1186/1476-4598-9-279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978147/
https://www.ncbi.nlm.nih.gov/pubmed/20958956
http://dx.doi.org/10.1186/1476-4598-9-279

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