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Inhibitors of inflammation and endogenous surfactant pool size as modulators of lung injury with initiation of ventilation in preterm sheep

BACKGROUND: Increased pro-inflammatory cytokines in tracheal aspirates correlate with the development of BPD in preterm infants. Ventilation of preterm lambs increases pro-inflammatory cytokines and causes lung inflammation. OBJECTIVE: We tested the hypothesis that selective inhibitors of pro-inflam...

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Detalles Bibliográficos
Autores principales: Hillman, Noah H, Kallapur, Suhas G, Pillow, J Jane, Nitsos, Ilias, Polglase, Graeme R, Ikegami, Machiko, Jobe, Alan H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978154/
https://www.ncbi.nlm.nih.gov/pubmed/21034485
http://dx.doi.org/10.1186/1465-9921-11-151