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Role of LOX-1 and ROS in oxidized low-density lipoprotein induced epithelial-mesenchymal transition of NRK52E

BACKGROUND: To investigate the effect of oxidized low density lipoprotein receptor-1 (LOX-1) on tubular epithelial-mesenchymal transition (TEMT) induced by oxidized low-density lipoprotein (ox-LDL) and its mechanism. METHODS: NRK-52E cells were incubated with ox-LDL (0, 25, 50, and 100 μg/ml) for 24...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Ding, Guohua, Liang, Wei, Chen, Cheng, Yang, Hongxia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978210/
https://www.ncbi.nlm.nih.gov/pubmed/20958994
http://dx.doi.org/10.1186/1476-511X-9-120