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Effects of creatine and β-guanidinopropionic acid and alterations in creatine transporter and creatine kinases expression in acute seizure and chronic epilepsy models

BACKGROUND: In order to confirm the roles of creatine (Cr) in epilepsy, we investigated the anti-convulsive effects of Cr, creatine transporter (CRT) and creatine kinases (CKs) against chemical-induced acute seizure activity and chronic epileptic seizure activity. RESULTS: Two hr after pilocarpine (...

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Detalles Bibliográficos
Autores principales: Kim, Dae Won, Yeo, Seong-Il, Ryu, Hea Jin, Kim, Ji-Eun, Song, Hong-Ki, Kwon, Oh-Shin, Choi, Soo Young, Kang, Tae-Cheon
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978220/
https://www.ncbi.nlm.nih.gov/pubmed/20979657
http://dx.doi.org/10.1186/1471-2202-11-141