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MHC allele frequency distributions under parasite-driven selection: A simulation model
BACKGROUND: The extreme polymorphism that is observed in major histocompatibility complex (MHC) genes, which code for proteins involved in recognition of non-self oligopeptides, is thought to result from a pressure exerted by parasites because parasite antigens are more likely to be recognized by MH...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978226/ https://www.ncbi.nlm.nih.gov/pubmed/20979635 http://dx.doi.org/10.1186/1471-2148-10-332 |