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Long-range effects of histone point mutations on DNA remodeling revealed from computational analyses of SIN-mutant nucleosome structures

The packaging of DNA into nucleosomes impedes the binding and access of molecules involved in its processing. The SWI/SNF multi-protein assembly, found in yeast, is one of many regulatory factors that stimulate the remodeling of DNA required for its transcription. Amino-acid point mutations in histo...

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Detalles Bibliográficos
Autores principales: Xu, Fei, Colasanti, Andrew V., Li, Yun, Olson, Wilma K.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978337/
https://www.ncbi.nlm.nih.gov/pubmed/20647418
http://dx.doi.org/10.1093/nar/gkq506