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All-codon scanning identifies p53 cancer rescue mutations

In vitro scanning mutagenesis strategies are valuable tools to identify critical residues in proteins and to generate proteins with modified properties. We describe the fast and simple All-Codon Scanning (ACS) strategy that creates a defined gene library wherein each individual codon within a specif...

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Detalles Bibliográficos
Autores principales: Baronio, Roberta, Danziger, Samuel A., Hall, Linda V., Salmon, Kirsty, Hatfield, G. Wesley, Lathrop, Richard H., Kaiser, Peter
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978351/
https://www.ncbi.nlm.nih.gov/pubmed/20581117
http://dx.doi.org/10.1093/nar/gkq571