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Pot1 inactivation leads to rampant telomere resection and loss in one cell cycle

Removal of the conserved telomere protein, Pot1, confers the immediate loss of fission yeast telomeres. This drastic phenotype has established the centrality of Pot1 for telomere maintenance but prohibited elucidation of the intermediate steps leading to telomere loss. To circumvent this problem, we...

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Detalles Bibliográficos
Autores principales: Pitt, Christopher W., Cooper, Julia Promisel
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978358/
https://www.ncbi.nlm.nih.gov/pubmed/20601686
http://dx.doi.org/10.1093/nar/gkq580