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Pot1 inactivation leads to rampant telomere resection and loss in one cell cycle
Removal of the conserved telomere protein, Pot1, confers the immediate loss of fission yeast telomeres. This drastic phenotype has established the centrality of Pot1 for telomere maintenance but prohibited elucidation of the intermediate steps leading to telomere loss. To circumvent this problem, we...
Autores principales: | Pitt, Christopher W., Cooper, Julia Promisel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978358/ https://www.ncbi.nlm.nih.gov/pubmed/20601686 http://dx.doi.org/10.1093/nar/gkq580 |
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