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Class-specific restrictions define primase interactions with DNA template and replicative helicase

Bacterial primase is stimulated by replicative helicase to produce RNA primers that are essential for DNA replication. To identify mechanisms regulating primase activity, we characterized primase initiation specificity and interactions with the replicative helicase for gram-positive Firmicutes (Stap...

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Detalles Bibliográficos
Autores principales: Larson, Marilynn A., Griep, Mark A., Bressani, Rafael, Chintakayala, Kiran, Soultanas, Panos, Hinrichs, Steven H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978363/
https://www.ncbi.nlm.nih.gov/pubmed/20591822
http://dx.doi.org/10.1093/nar/gkq588