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Class-specific restrictions define primase interactions with DNA template and replicative helicase
Bacterial primase is stimulated by replicative helicase to produce RNA primers that are essential for DNA replication. To identify mechanisms regulating primase activity, we characterized primase initiation specificity and interactions with the replicative helicase for gram-positive Firmicutes (Stap...
Autores principales: | Larson, Marilynn A., Griep, Mark A., Bressani, Rafael, Chintakayala, Kiran, Soultanas, Panos, Hinrichs, Steven H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978363/ https://www.ncbi.nlm.nih.gov/pubmed/20591822 http://dx.doi.org/10.1093/nar/gkq588 |
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