α-Actinin-4 Is Essential for Maintaining the Spreading, Motility and Contractility of Fibroblasts

BACKGROUND: α-Actinins cross-link actin filaments, with this cross-linking activity regulating the formation of focal adhesions, intracellular tension, and cell migration. Most non-muscle cells such as fibroblasts express two isoforms, α-actinin-1 (ACTN1) and α-actinin-4 (ACTN4). The high homology b...

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Detalles Bibliográficos
Autores principales: Shao, Hanshuang, Wang, James H.-C., Pollak, Martin R., Wells, Alan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978680/
https://www.ncbi.nlm.nih.gov/pubmed/21085685
http://dx.doi.org/10.1371/journal.pone.0013921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978680/
https://www.ncbi.nlm.nih.gov/pubmed/21085685
http://dx.doi.org/10.1371/journal.pone.0013921

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