Vulnerabilities in the Tau Network and the Role of Ultrasensitive Points in Tau Pathophysiology

The multifactorial nature of disease motivates the use of systems-level analyses to understand their pathology. We used a systems biology approach to study tau aggregation, one of the hallmark features of Alzheimer's disease. A mathematical model was constructed to capture the current state of...

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Detalles Bibliográficos
Autores principales: Yuraszeck, Theresa M., Neveu, Pierre, Rodriguez-Fernandez, Maria, Robinson, Anne, Kosik, Kenneth S., Doyle, Francis J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978700/
https://www.ncbi.nlm.nih.gov/pubmed/21085645
http://dx.doi.org/10.1371/journal.pcbi.1000997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978700/
https://www.ncbi.nlm.nih.gov/pubmed/21085645
http://dx.doi.org/10.1371/journal.pcbi.1000997

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