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Vulnerabilities in the Tau Network and the Role of Ultrasensitive Points in Tau Pathophysiology

The multifactorial nature of disease motivates the use of systems-level analyses to understand their pathology. We used a systems biology approach to study tau aggregation, one of the hallmark features of Alzheimer's disease. A mathematical model was constructed to capture the current state of...

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Detalles Bibliográficos
Autores principales:	Yuraszeck, Theresa M., Neveu, Pierre, Rodriguez-Fernandez, Maria, Robinson, Anne, Kosik, Kenneth S., Doyle, Francis J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978700/ https://www.ncbi.nlm.nih.gov/pubmed/21085645 http://dx.doi.org/10.1371/journal.pcbi.1000997

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