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An Evolutionary Framework for Association Testing in Resequencing Studies

Sequencing technologies are becoming cheap enough to apply to large numbers of study participants and promise to provide new insights into human phenotypes by bringing to light rare and previously unknown genetic variants. We develop a new framework for the analysis of sequence data that incorporate...

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Detalles Bibliográficos
Autores principales: King, C. Ryan, Rathouz, Paul J., Nicolae, Dan L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978703/
https://www.ncbi.nlm.nih.gov/pubmed/21085648
http://dx.doi.org/10.1371/journal.pgen.1001202