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Inhibition of Endothelin-1-Mediated Contraction of Hepatic Stellate Cells by FXR Ligand

Activation of hepatic stellate cells (HSCs) plays an important role in the development of cirrhosis through the increased production of collagen and the enhanced contractile response to vasoactive mediators such as endothelin-1 (ET-1). The farnesoid X receptor (FXR) is a member of the nuclear recept...

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Detalles Bibliográficos
Autores principales: Li, Jiang, Kuruba, Ramalinga, Wilson, Annette, Gao, Xiang, Zhang, Yifei, Li, Song
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978707/
https://www.ncbi.nlm.nih.gov/pubmed/21085652
http://dx.doi.org/10.1371/journal.pone.0013955