Mutations in the Polycomb Group Gene polyhomeotic Lead to Epithelial Instability in both the Ovary and Wing Imaginal Disc in Drosophila

BACKGROUND: Most human cancers originate from epithelial tissues and cell polarity and adhesion defects can lead to metastasis. The Polycomb-Group of chromatin factors were first characterized in Drosophila as repressors of homeotic genes during development, while studies in mammals indicate a conse...

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Detalles Bibliográficos
Autores principales: Gandille, Pierre, Narbonne-Reveau, Karine, Boissonneau, Elisabeth, Randsholt, Neel, Busson, Denise, Pret, Anne-Marie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978711/
https://www.ncbi.nlm.nih.gov/pubmed/21085656
http://dx.doi.org/10.1371/journal.pone.0013946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978711/
https://www.ncbi.nlm.nih.gov/pubmed/21085656
http://dx.doi.org/10.1371/journal.pone.0013946

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