Human Stem Cell-Derived Neurons: A System to Study Human Tau Function and Dysfunction

BACKGROUND: Intracellular filamentous deposits containing microtubule-associated protein tau constitute a defining characteristic of many neurodegenerative disorders. Current experimental models to study tau pathology in vitro do not usually recapitulate the tau expression pattern characteristic of...

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Detalles Bibliográficos
Autores principales: Iovino, Mariangela, Patani, Rickie, Watts, Colin, Chandran, Siddharthan, Spillantini, Maria Grazia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978712/
https://www.ncbi.nlm.nih.gov/pubmed/21085657
http://dx.doi.org/10.1371/journal.pone.0013947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978712/
https://www.ncbi.nlm.nih.gov/pubmed/21085657
http://dx.doi.org/10.1371/journal.pone.0013947

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