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Human Stem Cell-Derived Neurons: A System to Study Human Tau Function and Dysfunction
BACKGROUND: Intracellular filamentous deposits containing microtubule-associated protein tau constitute a defining characteristic of many neurodegenerative disorders. Current experimental models to study tau pathology in vitro do not usually recapitulate the tau expression pattern characteristic of...
Autores principales: | Iovino, Mariangela, Patani, Rickie, Watts, Colin, Chandran, Siddharthan, Spillantini, Maria Grazia |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978712/ https://www.ncbi.nlm.nih.gov/pubmed/21085657 http://dx.doi.org/10.1371/journal.pone.0013947 |
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