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Transient Increase in Cyclic AMP Localized to Macrophage Phagosomes

Cyclic AMP (cAMP) regulates many biological processes and cellular functions. The importance of spatially localized intracellular gradients of cAMP is increasingly appreciated. Previous work in macrophages has shown that cAMP is produced during phagocytosis and that elevated cAMP levels suppress hos...

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Detalles Bibliográficos
Autores principales: Ballinger, Megan N., Welliver, Timothy, Straight, Samuel, Peters-Golden, Marc, Swanson, Joel A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978719/
https://www.ncbi.nlm.nih.gov/pubmed/21085604
http://dx.doi.org/10.1371/journal.pone.0013962