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Hepatitis C Virus (HCV) Evades NKG2D-Dependent NK Cell Responses through NS5A-Mediated Imbalance of Inflammatory Cytokines

Understanding how hepatitis C virus (HCV) induces and circumvents the host's natural killer (NK) cell-mediated immunity is of critical importance in efforts to design effective therapeutics. We report here the decreased expression of the NKG2D activating receptor as a novel strategy adopted by...

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Detalles Bibliográficos
Autores principales: Sène, Damien, Levasseur, Franck, Abel, Michal, Lambert, Marion, Camous, Xavier, Hernandez, Céline, Pène, Véronique, Rosenberg, Arielle R., Jouvin-Marche, Evelyne, Marche, Patrice N., Cacoub, Patrice, Caillat-Zucman, Sophie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978723/
https://www.ncbi.nlm.nih.gov/pubmed/21085608
http://dx.doi.org/10.1371/journal.ppat.1001184