Characterization of a Novel SOD-1(G93A) Transgenic Mouse Line with Very Decelerated Disease Development

Amyotrophic Lateral Sclerosis (ALS) is a fatal motoneuron disease, characterized by progressive weakness, muscle wasting and death ensuing 3–5 years after diagnosis. The etiology of ALS is complex and therapeutic approaches rely mostly on transgenic animal models with SOD-1 mutations. Most frequentl...

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Detalles Bibliográficos
Autores principales: Henriques, Alexandre, Pitzer, Claudia, Schneider, Armin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978730/
https://www.ncbi.nlm.nih.gov/pubmed/21102999
http://dx.doi.org/10.1371/journal.pone.0015445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978730/
https://www.ncbi.nlm.nih.gov/pubmed/21102999
http://dx.doi.org/10.1371/journal.pone.0015445

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