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Characterization of a Novel SOD-1(G93A) Transgenic Mouse Line with Very Decelerated Disease Development
Amyotrophic Lateral Sclerosis (ALS) is a fatal motoneuron disease, characterized by progressive weakness, muscle wasting and death ensuing 3–5 years after diagnosis. The etiology of ALS is complex and therapeutic approaches rely mostly on transgenic animal models with SOD-1 mutations. Most frequentl...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978730/ https://www.ncbi.nlm.nih.gov/pubmed/21102999 http://dx.doi.org/10.1371/journal.pone.0015445 |