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Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast
Aneuploidy, referring here to genome contents characterized by abnormal numbers of chromosomes, has been associated with developmental defects, cancer, and adaptive evolution in experimental organisms1–9. However, it remains unresolved how aneuploidy impacts gene expression and whether aneuploidy co...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978756/ https://www.ncbi.nlm.nih.gov/pubmed/20962780 http://dx.doi.org/10.1038/nature09529 |