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C-terminal Binding Protein (CtBP) and Poly(ADP)ribose polymerase1 (PARP-1) contribute to repression of the p21(waf1/cip1) promoter

Transcriptional repression by the C-terminal Binding Protein (CtBP) is proposed to require NAD(H). Prior studies have implicated CtBP in transcriptional repression of the p21(waf1/cip1) gene. Similarly, the NAD-dependent Poly(ADP)ribose Polymerase (PARP1) may affect p21 expression via its NAD-depend...

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Detalles Bibliográficos
Autores principales: Madison, Dana L, Lundblad, James R
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978806/
https://www.ncbi.nlm.nih.gov/pubmed/20711239
http://dx.doi.org/10.1038/onc.2010.338