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C-terminal Binding Protein (CtBP) and Poly(ADP)ribose polymerase1 (PARP-1) contribute to repression of the p21(waf1/cip1) promoter
Transcriptional repression by the C-terminal Binding Protein (CtBP) is proposed to require NAD(H). Prior studies have implicated CtBP in transcriptional repression of the p21(waf1/cip1) gene. Similarly, the NAD-dependent Poly(ADP)ribose Polymerase (PARP1) may affect p21 expression via its NAD-depend...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978806/ https://www.ncbi.nlm.nih.gov/pubmed/20711239 http://dx.doi.org/10.1038/onc.2010.338 |