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Redox regulation of mitochondrial fission, protein misfolding, synaptic damage, and neuronal cell death: potential implications for Alzheimer’s and Parkinson’s diseases

Normal mitochondrial dynamics consist of fission and fusion events giving rise to new mitochondria, a process termed mitochondrial biogenesis. However, several neurodegenerative disorders manifest aberrant mitochondrial dynamics, resulting in morphological abnormalities often associated with deficit...

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Detalles Bibliográficos
Autores principales: Nakamura, Tomohiro, Lipton, Stuart A.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978885/
https://www.ncbi.nlm.nih.gov/pubmed/20177970
http://dx.doi.org/10.1007/s10495-010-0476-x