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Ethyl 6-[4-(dimethyl­amino)phen­yl]-4-hydr­oxy-2-oxo-4-(trifluoro­methyl)­hexa­hydro­pyrimidine-5-carboxyl­ate

The title compound, C(16)H(20)F(3)N(3)O(4), was prepared by reaction of 4-(dimethyl­amino)benzaldehyde, ethyl 4,4,4-trifluoro-3-oxo­butanoate and urea. In the title mol­ecule, the pyrimidine ring adopts a half-chair conformation and there is an intra­molecular hydrogen bond (O—H⋯O). The crystal stru...

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Detalles Bibliográficos
Autores principales: Song, Xiao-Ping, Li, Gong-Chun, Wu, Chang-Zeng, Yang, Feng-Ling
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2979242/
https://www.ncbi.nlm.nih.gov/pubmed/21579137
http://dx.doi.org/10.1107/S1600536810013127