DNA Sequence Profiles of the Colorectal Cancer Critical Gene Set KRAS-BRAF-PIK3CA-PTEN-TP53 Related to Age at Disease Onset

The incidence of colorectal cancer (CRC) increases with age and early onset indicates an increased likelihood for genetic predisposition for this disease. The somatic genetics of tumor development in relation to patient age remains mostly unknown. We have examined the mutation status of five known c...

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Detalles Bibliográficos
Autores principales: Berg, Marianne, Danielsen, Stine A., Ahlquist, Terje, Merok, Marianne A., Ågesen, Trude H., Vatn, Morten H., Mala, Tom, Sjo, Ole H., Bakka, Arne, Moberg, Ingvild, Fetveit, Torunn, Mathisen, Øystein, Husby, Anders, Sandvik, Oddvar, Nesbakken, Arild, Thiis-Evensen, Espen, Lothe, Ragnhild A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980471/
https://www.ncbi.nlm.nih.gov/pubmed/21103049
http://dx.doi.org/10.1371/journal.pone.0013978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980471/
https://www.ncbi.nlm.nih.gov/pubmed/21103049
http://dx.doi.org/10.1371/journal.pone.0013978

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