Suppression of TGFβ-Induced Epithelial-Mesenchymal Transition Like Phenotype by a PIAS1 Regulated Sumoylation Pathway in NMuMG Epithelial Cells

Epithelial-mesenchymal-transition (EMT) is a fundamental cellular process that is critical for normal development and tumor metastasis. The transforming growth factor beta (TGFβ) is a potent inducer of EMT like effects, but the mechanisms that regulate TGFβ-induced EMT remain incompletely understood...

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Detalles Bibliográficos
Autores principales: Netherton, Stuart J., Bonni, Shirin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980481/
https://www.ncbi.nlm.nih.gov/pubmed/21103059
http://dx.doi.org/10.1371/journal.pone.0013971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980481/
https://www.ncbi.nlm.nih.gov/pubmed/21103059
http://dx.doi.org/10.1371/journal.pone.0013971

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