Amplicon-Dependent CCNE1 Expression Is Critical for Clonogenic Survival after Cisplatin Treatment and Is Correlated with 20q11 Gain in Ovarian Cancer

Genomic amplification of 19q12 occurs in several cancer types including ovarian cancer where it is associated with primary treatment failure. We systematically attenuated expression of genes within the minimally defined 19q12 region in ovarian cell lines using short-interfering RNAs (siRNA) to ident...

Descripción completa

Detalles Bibliográficos
Autores principales: Etemadmoghadam, Dariush, George, Joshy, Cowin, Prue A., Cullinane, Carleen, Kansara, Maya, Gorringe, Kylie L., Smyth, Gordon K., Bowtell, David D. L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980490/
https://www.ncbi.nlm.nih.gov/pubmed/21103391
http://dx.doi.org/10.1371/journal.pone.0015498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980490/
https://www.ncbi.nlm.nih.gov/pubmed/21103391
http://dx.doi.org/10.1371/journal.pone.0015498

Ejemplares similares