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Anti-angiogenic effects of resveratrol mediated by decreased VEGF and increased TSP1 expression in melanoma-endothelial cell co-culture

Resveratrol, a naturally occurring polyphenol, has been reported to be an anti-tumor and chemopreventive agent. Recent data show that it may also exert anti-angiogenic effects. We hypothesized that the anti-angiogenic activity of resveratrol may be caused by modulation of tumor cell release of throm...

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Detalles Bibliográficos
Autores principales: Trapp, Valerie, Parmakhtiar, Basmina, Papazian, Vartan, Willmott, Lyndsay, Fruehauf, John P.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980626/
https://www.ncbi.nlm.nih.gov/pubmed/20927579
http://dx.doi.org/10.1007/s10456-010-9187-8