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Extensive Co-Operation between the Epstein-Barr Virus EBNA3 Proteins in the Manipulation of Host Gene Expression and Epigenetic Chromatin Modification

Epstein-Barr virus (EBV) is able to drive the transformation of B-cells, resulting in the generation of lymphoblastoid cell lines (LCLs) in vitro. EBV nuclear proteins EBNA3A and EBNA3C are necessary for efficient transformation, while EBNA3B is dispensable. We describe a transcriptome analysis of B...

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Detalles Bibliográficos
Autores principales: White, Robert E., Groves, Ian J., Turro, Ernest, Yee, Jade, Kremmer, Elisabeth, Allday, Martin J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981562/
https://www.ncbi.nlm.nih.gov/pubmed/21085583
http://dx.doi.org/10.1371/journal.pone.0013979