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Cystatin C Deficiency Promotes Epidermal Dysplasia in K14-HPV16 Transgenic Mice

BACKGROUND: Cysteine protease cathepsins are important in extracellular matrix protein degradation, cell apoptosis, and angiogenesis. Mice lacking cathepsins are protected from tumor progression in several animal models, suggesting that the regulation of cathepsin activities controls the growth of v...

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Detalles Bibliográficos
Autores principales: Yu, Weifang, Liu, Jian, Shi, Michael A., Wang, Jianan, Xiang, Meixiang, Kitamoto, Shiro, Wang, Bing, Sukhova, Galina K., Murphy, George F., Orasanu, Gabriela, Grubb, Anders, Shi, Guo-Ping
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981574/
https://www.ncbi.nlm.nih.gov/pubmed/21085595
http://dx.doi.org/10.1371/journal.pone.0013973