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Cystatin C Deficiency Promotes Epidermal Dysplasia in K14-HPV16 Transgenic Mice
BACKGROUND: Cysteine protease cathepsins are important in extracellular matrix protein degradation, cell apoptosis, and angiogenesis. Mice lacking cathepsins are protected from tumor progression in several animal models, suggesting that the regulation of cathepsin activities controls the growth of v...
Autores principales: | Yu, Weifang, Liu, Jian, Shi, Michael A., Wang, Jianan, Xiang, Meixiang, Kitamoto, Shiro, Wang, Bing, Sukhova, Galina K., Murphy, George F., Orasanu, Gabriela, Grubb, Anders, Shi, Guo-Ping |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981574/ https://www.ncbi.nlm.nih.gov/pubmed/21085595 http://dx.doi.org/10.1371/journal.pone.0013973 |
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