Genomic Runs of Homozygosity Record Population History and Consanguinity

The human genome is characterised by many runs of homozygous genotypes, where identical haplotypes were inherited from each parent. The length of each run is determined partly by the number of generations since the common ancestor: offspring of cousin marriages have long runs of homozygosity (ROH),...

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Detalles Bibliográficos
Autores principales: Kirin, Mirna, McQuillan, Ruth, Franklin, Christopher S., Campbell, Harry, McKeigue, Paul M., Wilson, James F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981575/
https://www.ncbi.nlm.nih.gov/pubmed/21085596
http://dx.doi.org/10.1371/journal.pone.0013996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981575/
https://www.ncbi.nlm.nih.gov/pubmed/21085596
http://dx.doi.org/10.1371/journal.pone.0013996

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